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Tuesday, January 01, 2019 2:36:16 AM
“Our bioceramics are biodegradable, or they can be engulfed through cells,” Varanasi explains. “The intent in the end is to rapidly deliver the therapeutic, induce the healing at an earlier point, and then allow the cells and the tissue to overtake the material, consume the material, and allow for full restoration of natural bone.
It’s a concept that has generated promising results since testing began on animal models in spring 2015. To date, the chemical makeup of the new bone has been found to be comparable to the bone surrounding the defect.
To help such advance to that next level, Varanasi and the Texas A&M Office of Technology Commercialization have been in talks with potential investors. Proposals for commercialization and scientific research grants with National Institutes of Health, National Science Foundation, the Department of Defense, and collaborations with industry will be pursued.
“By combining the expertise of our colleagues in biomedical sciences within the bioengineering core, there is a future of possibly creating a bioengineered prosthesis, rebuilding the anatomy with a ‘bio-active’ material,” says Suzanne Verma, anaplastologist and assistant professor in oral and maxillofacial surgery at the dental school.
The company entered a multi-year agreement with Texas A&M University's School of Dentistry to evaluate silicon nitride in maxillofacial surgery, where osteogenic and antimicrobial properties are highly desirable. This partnership is expected to yield funding from the U.S. National Institute of Health (NIH) and the Small Business Innovative Research (SBIR) programs to continue support for Amedica's R&D efforts.
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