Elite Pharmaceuticals Inc (ELTP)

[WeeZuhl]

It's all relative.






Nothing in either of your posts disputes the science of isradipine over all other CCB's for PD. Isradipine has the highest affinity for CaV1.3 relative to CaV1.2. All other CCBs, even those which cross the blood brain barrier and have some affinity for CaV1.3, are inferior to isradipine because of the higher affinity for CaV1.3 vs. CaV1.2. That means any other CCB is more likely to lower a patient's blood pressure, even if it is neuroprotective. That's why isradipine is the **ONLY** CCB to have a Phase 2 and Phase 3 study for Parkinson's Disease. And that's why isradipine will be the **ONLY** CCB that will be Rx'ed for PD.