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Re: eskay1954 post# 14030

Tuesday, 11/13/2018 2:31:11 PM

Tuesday, November 13, 2018 2:31:11 PM

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Re: the similar SOFA score results (and I'm not a doctor or researcher), but the way I read the conclusion of the study hyperlinked below, any reduction in "big endothelin-1" looks to be a very desirable outcome:

"In a large population of patients with symptomatic heart failure, the circulating concentration of Big ET-1, a precursor of the paracrine and bioactive peptide ET-1, was an independent marker of mortality and morbidity. In this setting, BNP remained the strongest neurohormonal prognostic factor."

https://www.ncbi.nlm.nih.gov/pubmed/16762801

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