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Re: XenaLives post# 7242

Saturday, 11/10/2018 3:01:07 PM

Saturday, November 10, 2018 3:01:07 PM

Post# of 21544

They must know the protocol and there must be a good reason for not disclosing it.



They must know the protocol and there must be “a” reason for not disclosing it.

I can’t think of a single “good” reason though.

“Trial Registration

Why is Trial Registration Important?

The registration of all interventional trials is considered to be a scientific, ethical and moral responsibility because:

There is a need to ensure that decisions about health care are informed by all of the available evidence

It is difficult to make informed decisions if publication bias and selective reporting are present

The Declaration of Helsinki states that "Every clinical trial must be registered in a publicly accessible database before recruitment of the first subject".

Improving awareness of similar or identical trials will make it possible for researchers and funding agencies to avoid unnecessary duplication

Describing clinical trials in progress can make it easier to identify gaps in clinical trials research

Making researchers and potential participants aware of recruiting trials may facilitate recruitment

Enabling researchers and health care practitioners to identify trials in which they may have an interest could result in more effective collaboration among researchers. The type of collaboration may include prospective meta-analysis

Registries checking data as part of the registration process may lead to improvements in the quality of clinical trials by making it possible to identify potential problems (such as problematic randomization methods) early in the research process

http://www.who.int/ictrp/trial_reg/en/

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