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Sunday, October 21, 2018 11:30:06 AM
Polymedix recorded astonishing > 90% reduction of SOM in mice. Granted, it is mice we are talking. Still, the reduction was achieved with brilacidin pouch stuffed in rodential cheeks. That provides longer contact time with mucosa than any reasonable oral rinse. How are we going to do that with humans? Ask them keep big pouches in their cheeks day after day?
Hehheh... might make them look adorably cheeky... but NO.
Sticky slowly dissolving tablet a la Validive is possibility. I happen to think the best solution is to inhibit proinflammatory interleukins as early as possible via IV. Especially if it can be shown that IV once a week is sufficient.
My main point: BP has several very talented scientists at its disposal. I would be really surprised if those scientists think that the level of efficacy achieved by IPIX is the end of development process.
"I would rather have questions that can't be answered than answers that can't be questioned." Richard P. Feynman
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