Tocagen Inc (TOCA)

[gr8db8]

Common considerations for immuno-oncology drugs include objective response rates in a select subset of patients with prolonged duration of response, a delayed separation, and a late plateau of survival curves, as well as a median overall survival that may obscure the long-term benefits in the minority of patients with responses.38 Therefore durable response rate may represent a new and clinically meaningful surrogate endpoint for overall survival in brain cancer trials, to more accurately assess clinical benefit of novel immune-oncology drugs for the treatment of brain tumors.