SiNtx Technologies Inc (SINT)

[SmokerX]

Not sure. I`m no expert, nor do I know anyone using products so I can only speak anecdotally. I know I was reading something about manufacture and they where talking about crushing us seashells. I know I was reading something years back of people implanting coral plugs on their skull and it fusing into horns. I know I've read within the cadaver products own literature it's a vector for disease.

Using human bone carries a similar level of risk of transmitting infectious disease to receiving blood from the blood bank.

Cow bone has been commonly used for many years. It is sterilized and processed to minimize infection, but like human cadaver bone, there is the possibility of contamination.

Although less-effective than the other options, these sterile bone-like materials are second only to a patient’s own bone in terms of safety.

https://www.dentalimplantcostguide.com/dental-bone-graft/

Also, I think there's religious hurdles to using cadaver bone in some patients. The one person I know who received a bone graft it was cadaver. I know any surgery in the mouth looks like it's an area of extreme risk to infection. When it goes wrong, it really goes wrong. for instance a patient received oral surgery an infection led to osteomyelitis of the lower jaw. The entire lower jaw had to be removed and replaced with a custom 3d printed implant. As well as rejection of the implants in dental causing bone to recede being equally disastrous.

I can poke in the dark of this bioglass 45S5. Originally developed to fill a hole in MASH units in Korea. Why where they not just flying in cadaver or cow bone graft? Guys would come in with their limbs so badly blown apart They needed a big piece of bone graft to fill the void that would allow for the bone plate to secure the two remaining pieces back together. Without there would be loss of limb. This seems like an area that would benefit greatly from increased strength of the porous scaffold(as well as antibacterial properties)

Then I`d like to reference a case study I've posted. a metal hip implant in a canine thrown in the trash on the 3rd surgery. The unit totaled $2,500 for just the implant manufacturer into the trash it goes. Was this due to infection or a Foreign body reaction? Who knows? Nothing was sent out for culture to find out.
Nobody seemed too worried about the cost of 3 surgeries and throwing away a $2,500 hand full of trash there. If I where the dog owner forking this out of pocket I would rate this a complete failure. Given the option I would pay a little extra to not loose my bottom jaw and probably save a ton on revision surgeries. Doesn't matter if it's cheaper in the short term if it doesn't work and gets thrown in the trash with the hip analogy. At that point why dont you just shove a handful of wadded up news paper in there and call it a day and save me the $2,500.