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Re: Samsa post# 36943

Friday, 09/28/2018 10:44:55 AM

Friday, September 28, 2018 10:44:55 AM

Post# of 38634
I don't know how to be more clear...



On the other hand your assertions here that IPCI will not make Oral abuse because the drug can be chewed is ridiculous. You know better than that or at least should. The fact it can be chewed like bubblegum is not an issue. I already posted the guideline for oral abuse and being able to be chewed is not one of them. It comes down to how much of the drug is released upon manipulation such as pulverization, crushing, grinding etc. So as long as an acceptable amount of oxy is not released when chewed they will be fine.






...so I am typing this very slowly. I definitely do not think it will be considered a positive attribute that it can be chewed, but that is not why I think it will fail chewing studies. For about the zillionth time, all PEO-based drugs dose dump when chewed or pulverized. There is absolutely no reason to believe Rexista is any different than any other PEO-based drug, especially since the company is claiming they never tested for it. If they never tested it, then they certainly never designed for it. It's okay to be hopeful if you want, but it is not a hope based on any available information or rational thought process. Similar to: I hope the blue dye is not a problem. I hope to get results by mid year. I hope he doesn't dilute any more. I hope we get a partnership. I hope this new China company belongs to IPCI. I hope there is no reverse split.


Hope is all there is. How's that working out?


I hope I've typed this slowly enough.











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