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Re: Gametheory101 post# 1404

Monday, 10/30/2006 8:36:41 AM

Monday, October 30, 2006 8:36:41 AM

Post# of 12660
The enrollment pattern for 9902b would not be as back-loaded as in other trials. A large number were already enrolled when they switched to all GS and all 70 trial centers were up and running at that time. So from late 2005 to whenever enrollment ends in 2007, the enrollment rate should be steady with maybe some spikes around times with heavy publicity. With sicker patients, the median OS will not be as robust as in 9901, assuming some benefit for cross-over, probably around 16 months for placebos. So assuming a 75% event goal, getting results in 2008 isn't a stretch.
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