Avid Bioservices Inc (CDMO)

[drragmop]

"Mycobacterium tuberculosis, the causative agent of pulmonary tuberculosis, infects one-third of the world’s population (1). It accounts for more deaths each year than any other single infectious bacteria (2). Its ability to survive and replicate in the host macrophage is critical to its pathogenesis, emphasizing a need for a clearer understanding of its interactions with the host macrophage. In vitro experimental models have demonstrated that M. tuberculosis infection causes apoptosis of host macrophages. This has been demonstrated by the detection of annexin V binding to surface-exposed phosphatidylserine early after infection with M. tuberculosis."

http://www.jimmunol.org/cgi/content/full/170/1/430