Innovation Pharmaceuticals Inc (IPIX)

[PlentyParanoid]

MackG, What you say would work if the p2b trial would have been your usual orderly clinical trial. We have ample evidence that it was not.

I hazard a guess that last summer IPIX/CRO had sizable gaps in data from early enrollment making inference impossible - a situation where you can't absolutely rule out that you are looking at unblinded data comprised mostly of subjects on prurisol (or placebo). Plus not having a complete info from early enrollment would have made any interim report an exercise in futility:

"We are reporting interim results based on a non-random sample covering about 45 % of the subjects (70 % of enrollment) that have completed the treatment so far. Arms are not yet as balanced as we hope they will be in the final report ..." ---> Red hot roar from certain corners of STAT/TheStreet: "LEO IS CHERRY PICKING DATA !!!!!!!!!" And they would have been justified (well, sorta).

As I said, just a guess. But, the fact that they DID NOT CAN the trial then and there gives me some hope. As far as I know clinical trial contracts with CROs usually include some kind of early termination clause(s).