IPIX is going to payoff longs very soon $$, I'm very confident, I've been in the industry over 20 years and been part of many successful buyouts (biggest thus far PCYC/ AbbVie... I've done my homework and there is a buyout imminent, BP knows B-OM and Brilacidin itself (ABSSI) is a Franchise Blockbuster with all the unmet needs it can satisfy across numerous large market disease states.
Plaque Psoriasis treatment (Prurisol) is another MULTI Billion dollar a year market, with ALL THE advantages of PURISOL being a Non Biologic and Oral, newly diagnosed patients every year and large numbers of second line patients that fail the other treatments over time (resistance and Adverse Events ... e.g. (Ortezla - not to mention Ortezla's major AE - DEPRESSION). I expect the Prurisol data will be amazingly safe and highly efficacious based on preliminary public data already out there.
Look at the BMS press release today - September 12, 2018, there is High interest in the Plaque Psoriasis Market,
"Bristol-Myers plaque psoriasis drug shows promise in mid-stage trial.
(Reuters) - Bristol-Myers Squibb said on Wednesday its experimental drug helped reduce the severity of the most common form of psoriasis in a mid-stage trial.
The study tested the drug, BMS-986165, in 267 patients with plaque psoriasis, a chronic condition that causes dry, red skin lesions covered with silvery scales.
After 12 weeks, between 67 percent and 75 percent of patients given a 3-milligram dose twice daily, or a higher dose, showed reduction on a scale called PASI-75 that is considered the benchmark of main goals for most psoriasis clinical trials.
The PASI-75 scale showed reduction versus 7 percent in the placebo group. It measures the effectiveness of a drug by recording how many patients achieve a reduction in the area affected and severity of their psoriasis.
The drug is a tyrosine kinase 2 inhibitor, a class of medicines that work to regulate overactive immune responses that drive autoimmune diseases.
Three cases of serious side effects were reported, but none of those were in patients given the 6-mg and the 12-mg doses, the highest being tested, the company said.
Bristol-Myers said it plans to study the drug's use in a "wide spectrum of immune-mediated diseases", saying currently only few oral treatment options are available.
The company is currently enrolling patients for a late-stage trial and also testing BMS-986165 for use in patients with lupus or Crohn's disease.
An approval by the U.S. Food and Drug Administration for the plaque psoriasis treatment will offer Bristol-Myers, which relies heavily on its blockbuster cancer drug Opdivo, a chance to diversify its portfolio.
The FDA earlier this year declined to approve Bausch Health Cos Inc's plaque psoriasis lotion Duobrii and analysts now expect that drug to hit market only after 2019."
"In dermatology, the current focus is on managing Psoriasis with Prurisol. For cancer, the emphasis is on Ovarian Carcinomas, a gateway indication toward Kevetrin treating many other types of hematological malignancies and tumors. In the area of infectious disease, Acute Bacterial Skin and Skin Structure Infection (ABSSSI) is the target indication. As to gastrointestinal conditions, a study is underway evaluating Brilacidin's anti-microbial and anti-inflammatory properties in treating Inflammatory Bowel Disease. Brilacidin is also being tested in Oral Mucositis."
