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Re: runncoach post# 6842

Tuesday, 09/11/2018 9:29:39 PM

Tuesday, September 11, 2018 9:29:39 PM

Post# of 21507
Does anyone know if Huntington's Disease is a potential disease target for Bryostatin?

I'm reading in wikipedia that HDAC inhibitors are being investigated in this disease, and I think coach posted something about HDAC being involved in Alzheimer's.

https://en.wikipedia.org/wiki/Huntington%27s_disease )

"Among the approaches aimed at improving cell survival in the presence of mutant huntingtin are correction of transcriptional regulation using histone deacetylase inhibitors, modulating aggregation of huntingtin, improving metabolism and mitochondrial function and restoring function of synapses.[133]"

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