Friday, September 07, 2018 2:10:06 PM
Psoriasis
Recently we saw Can-Fite enrolled its first patient into the Phase III Plaque Psoriasis study.
What I note here is that the previous Phase II/III Plaque Psoriasis study of 293 - 325 (dependent on your source) patients appears to have taken almost 4 years from July 2011 to March 2015.
https://clinicaltrials.gov/ct2/show/NCT01265667?term=CF101&rank=6
https://ir.canfite.com/all-sec-filings/content/0001213900-17-000116/f6k010617ex99i_canfite.htm??TB_iframe=true&height=auto&width=auto&preload=false
The current Phase III Plaque Psoriasis study is due to enroll 407 patients, which is even more than the Phase II/III study, yet, the timeline noted for this study is to be completed by latest December 2019, meaning only 1 and a half years for enrollment and trial completion.
https://clinicaltrials.gov/ct2/show/NCT03168256?term=CF101&rank=2
I'm quite curious if the current Phase III trial is correctly expected to be completed in 1.5 years and if there is any rationale as to why it is expected to be completed with such greater speed than the prior Phase II/III study?
RA
On a similar curiosity, with regards the RA Phase III trial, this is meant to be completed by January-June 2019, having started October 2017. The study is due to enroll 525 patients.
The Phase II RA study, took 3 years and enrolled 79 patients.
Would we feel completing this RA Phase III study in 1.5 years with that many patients to be somewhat ambitious too?
Thanks for any input from those who've been with Can-Fite for longer than myself
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