Innovation Pharmaceuticals Inc (IPIX)

[MinnieM]

After reviewing PlentyParanoid's comment a bit closer, I'd have to agree with you that Palifermin isn't an actual radioprotective and may simply be used as a point of reference. Brilacidin couldn't fill that spot since it isn't approved yet.

https://investorshub.advfn.com/boards/read_msg.aspx?message_id=143197565

Maybe the emphasis on radioprotection has something to do with the scope of the article.

Amifostine and RRx-001 both originate from military radioprotective research. GC4419, a superoxide dismutase, has direct radioprotective properties by snubbing (not a scientific term, yet. I am working on it) superoxide radicals produced by radiation. Palifermin is not an actual radioprotective, but it is the only FDA approved drug for oral mucositis and probably serves as reference for the others. Excluded drugs, Dusquetide, Brilacidin, Validive, Epicatechin (EC-18) and AGO13 are more active in damage repair than in direct radioprotection.

Regarding movies... I've been trying to catch up on various DC and Marvel comic movies/series. Loosely keeping them in an order that allows me to get historical reference to various characters. My son got me hooked on this venture and it's a marvelous distraction in between things of more importance.






In Reply to 'loanranger'
"Allow me to show my ignorance"

I guess I did, didn't I? Apologies for the suggestion that you were exhibiting a bias.

I was thrown a bit by the appearance of the "/" in this quote:
"four clinical stage radioprotectors/chemoprotectors, amifostine, palifermin, GC4419 and RRx-001".

The title ("A Review of Clinical Radioprotection and Chemoprotection for Oral Mucositis") suggested to me that they were two different things. Plenty Paranoid mentioned that "Palifermin is not an actual radioprotective, but it is the only FDA approved drug for oral mucositis and probably serves as reference for the others."
I said to you "Allow me to show my ignorance by asking if Palifermin provides Radioprotection." You responded "Yes, as can be seen in the abstract." (as if I could follow the abstract).

Based on PP's comment it seems that Brilacidin could have been in the mix on the same basis...as a frame of reference....especially given its use on head and neck cancers, while Palifermin has not been approved for use in head and neck cancers.

Hope you enjoyed your movie.