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Tuesday, 08/21/2018 10:47:05 PM

Tuesday, August 21, 2018 10:47:05 PM

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An added advantage of post-formation insertion of 3D-PHAD® is that the amount of adjuvant per virosome can be halved.

Conclusions Stable 3D-PHAD® adjuvanted RSV virosomes can be formulated.

Measured by SPT, virosomes were stable for 300 days.

Purpose Characterization of virosomes, in late stage preclinical development as vaccines for Respiratory Syncytial Virus (RSV), with a membrane-incorporated synthetic monophosphoryl lipid A, 3D-PHAD® adjuvant.

Development of a Virosomal RSV Vaccine Containing 3D-PHAD® Adjuvant: Formulation, Composition, and Long-Term Stability
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