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Sunday, 08/19/2018 12:28:23 AM

Sunday, August 19, 2018 12:28:23 AM

Post# of 20689
Updated patent application on WIPO PATENTSCOPE

"2. 3356561 THERAPEUTIC AND DIAGNOSTIC METHODS FOR AUTOIMMUNE DISEASES AND/OR INFLAMMATION EP 08.08.2018
C12Q 1/68

16852729 MOMENTA PHARMACEUTICALS INC WASHBURN NATHANIEL
The present invention features methods of treating a subject having an autoimmune disease and/or inflammation including determining the genotype, and/or the glycophenotype of the subject and administering to the subject an Fc-activity modulating agent or an anti-TNFa agent based on the genotype and/or the glycophenotype of the subject. The invention also features methods of predicting the responsiveness of a patient to an anti-TNFa treatment by identifying a patient having inflammation or an autoimmune disease, determining the genotype, or glycophenotype of the subject, and selecting the patient for treatment with an Fc-activity modulating agent or an anti-TNFa agent based on the genotype and/or the glycophenotype of the subject."

detail.jsf

Note this,

"54. The method of any one of claims 43-53, wherein said autoimmune disease is rheumatoid arthritis (RA), juvenile RA, polyarticular-course juvenile RA, juvenile idiopathic arthritis, psoriasis, psoriatic arthritis, Crohn's Disease, ulcerative colitis, ankylosing spondylitis, plaque psoriasis, multiple sclerosis, systemic lupus erythematosus, myasthenia gravis, juvenile onset diabetes, glomerulonephritis, autoimmune thyroiditis, Behcet's disease, graft rejection, graft-versus-host disease, Kawasaki's disease, sarcoidosis, pyoderma gangrenosum, depression, bronchial asthma, diabetes mellitus, malignancies, septic shock, bullous dermatitis, neutrophilic dermatitis, toxic epidermal necrolysis, systemic vasculitis, pyoderma gangrenosum, pustular dermatitis, alcoholic hepatitis, cerebral malaria, hemolytic uremic syndrome, pre-eclampsia, allograft rejection, uveitis, otitis media, snakebite, erythema nodosum, myelodysplastic syndromes, dermatomyositis, polymyositis, immune reconstitution inflammatory syndrome of AIDS patients, systemic sclerosis, lgG4-related disease, or alopecia areata.”

Oh Boy, snakebite, malaria and inflammatory syndrome of AIDS patients included. Asthma has the most people with problems. Almost 7 million i read this week.

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