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Re: slcimmuno post# 232970

Monday, 08/06/2018 9:04:27 PM

Monday, August 06, 2018 9:04:27 PM

Post# of 403047
Great DD sicimmuno, The Otezla P2 12 week study is what were aiming for.

Pulled Otezla/Apremilast Ph2 results... 24% Active vs 10% Placebo PASI 75

PRU gets anywhere close to this spread (e.g., 21/10, 23/13, 22/11, even 19/9) and think IPIX has a winner, a Partnerable drug ---- CELG was later able to get Otezla efficacy up into the high 20s/low 30s, across 16 weeks (ours is 12 weeks, like in this Otezla Ph2) so efficacy slope will be worth watching -- did effect plateau at 12 weeks or is it still on the climb (ie, 16 weeks and we get even better numbers)

At least that's what I'm hoping - comparable results to Otezla at same stage...


My opinion.

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