Mymetics Corp (MYMX)

[TheHungryHippo]

Spray drying of virosomes to produce stable vaccines

Conclusions

Virosomes were successfully spray dried into three dry powder formulations, designed for oral and nasal drug delivery.

The integrity of the virosome structure and antigen reactivity was maintained after spray drying and processing parameters could influence the physical powder.

An enteric-coated oral capsule to deliver the formulation to the Peyer’s patch-rich ileac region of the small intestine, and a single dose nasal spray have been developed.

Studies are currently being conducted to assess the long-term stability of the powder. The efficacy and safety is currently being evaluated in preclinical studies.

http://www.upperton.com/images/pdf/t10.pdf