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hTTps://seekingalpha.com/news/3375276-european-court-makes-restrictive-ruling-genome-editing?dr=1#email_link

European Court makes restrictive ruling on genome editing

The European Association for Bioindustries says the ruling contradicts a previous document that states precise gene editing technology (e.g., CRISPR/Cas9) may not need to be strictly regulated


Stephan Grupp, MD, PhD

Upfront Car T soon.

In both diseases, he highlights the potential for using these therapies outside of the currently recommended criteria, for example in the frontline setting or in ultra high-risk disease.

BCMA targeting represents a new area for CAR T-cells, and Dr Grupp emphasizes the importance of these positive findings in MM and other hematological malignancies.

1st line.

Next generation sequencing

CRS appears to increase in proportion with disease severity. However, in lymphoma overall toxicity is generally lower, though there does seem to be increased toxicity with axicabtagene ciloleucel compared to tisagenlecleucel.

Kymriah less toxic than Yescarta in DLBCL