Sunday, July 22, 2018 7:42:15 PM
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=139832035
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=139831664
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=138068621
Especially the one behind the first link gives a very succinct rapport of the (then only suspected) mechanism. The important point probably is that D-1MT would "only" be one of the many helpers that could work against (or actually avoid) a Treg overhang. There are many other approaches against Treg (e.g. low dose cyclophosphamide or low dose temozolomide), but IMHO D-1MT would be relatively charming, since it doesn't kill Tregs, but biases the progenitors to become Th17 instead of Treg.
As I said, it'd be an interesting thread _after_ Pisces is enrolled and completed, not before. And, what I do not know: would Oncosec be able to use 1MT (which is a racemer of D-1MT and L-1MT) without asking a third company? At least D-1MT is still patent protected (on the positive side: this means it's still being researched upon). [I have no idea if there is a method of use patent. Since 1MT is actually so old that it's no longer patented]
In the end, I think, it's something you have to ask someone who currently works at Oncosec when meeting them im person. It'd be a little off-putting if we all started to call or write mails about 1MT. They certainly are busy with more relevant things for us.
Have a good start into the new week!
dM
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