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Saturday, 07/21/2018 10:50:25 AM

Saturday, July 21, 2018 10:50:25 AM

Post# of 27434
Therapy for prescription drug overdose and opioids

Everyone is probably aware from the new of the increasing opioid epidemic here in the US, however prescription drug abuse is also a serious and growing problem in the United States. In the US alone, an estimated 54 million people over the age of 12 have used prescription drugs for nonmedical reasons.

This study which was conducted by the Fraunhofer Institute in Rostock Germany last year was published and recently uploaded, shows how Cytosorb can also help in the removal of some of these agents. Frauhofer has been one of the key study centers for Cytosorb for the last several years.

http://cytosorb-therapy.com/wp-content/uploads/2018/02/2017_Koertge_Poster_ESAO.pdf

Results:

Considerable removal of amitriptyline, diazepam, digoxin, quetiapine, and rivaroxaban was observed: 87.7 to 96.9 % of these administered drugs was rapidly removed from the blood, predominantly within 30 to 60 min of hemoperfusion, resulting in plasma levels near, within or below the respective therapeutic concentration range.

Paracetamol, ibuprofen, and amiodarone plasma concentrations were only decreased to a limited extent with 13.5, 45.4-59.5, and 50.2% removed mass, respectively. A decrease to and below the respective therapeutic concentration range could not be achieved for these substances.
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