Innovation Pharmaceuticals Inc (IPIX)

[PlentyParanoid]

KMBJN, I agree on both points. One 'questionable' refinement though. In terms of confidence limits for sPGA 0/1 shift 2 proportion (sPGA 0/1 for short) in prurisol p2a trial. If we assume success being sPGA 0/1 score 25 %, then one can say with 72 % confidence that based on the sample used in prurisol phase 2a trial the 'true' sPGA 0/1 response proportion for subjects with baseline sPGA score 3 is above 25 %.

Using some ad hoc sensitivity analysis on confidence limits I concluded that the odds of failure of in p2b trial are from 25 % to 45% with best estimate of 30 %. Not that much different from you estimate.