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BonelessCat

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BonelessCat

Re: To infinity and beyond! post# 233905

Monday, 07/09/2018 9:57:39 AM

Monday, July 09, 2018 9:57:39 AM

Post# of 403017
The bridge study was designed to show similar safety to Ziagen. The FDA accepted that. The mouse studies showed dose dependent efficacy. It’s not unusual for humans to require greater quantities of drug (gms/kg) to show the same therapeutic benefit. Again, we will know soon enough, but so far all evidence points to the same dose dependence with safety expected to exceed 600 mg. The current trial didn’t exceed 400 mg. Ziagen administration is 1100 mg, if I remember correctly. Correct me if I’m wrong.

* Never borrow to invest.

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