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Saturday, October 21, 2006 9:08:18 PM
BTW, just guessing here, but I think there's a pretty fair chance that 800 mg BID for 3 weeks is beyond what is currently allowed by the FDA's dosing restrictions. That dose was at the highest end of BID dosing in the Phase 1, where Cortex stopped dose escalations and called it MTD. Single dose MTD was 1600 mg. Further speculation on the dosing restriction topic is really somewhat pointless without having some additional info from Stoll, since we currently have next to nothing to go on.
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