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Re: walldiver post# 1322

Saturday, 10/21/2006 9:46:51 AM

Saturday, October 21, 2006 9:46:51 AM

Post# of 12660
In a survival analysis, median is defined as the point where the curve crosses the 50% point on the probability axis. Without censoring, that coincides with the normal median. But with censoring, it can shift to the right of the normal median by a significant amount. So the 10 people censored before the previous median of 25.9 months would shift the curve right quite a bit resulting in the current larger median.

This is actually the same issue with Dr. Gold's previous statement about the survival rates at 24 months of patients in the Taxotere trials. He forgot that significant censoring was going on in the Tax trials so looking only at the number of survivors at a certain time relative to the starting number would be wrong. It is good that he has dropped any reference to that in recent presentations.
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