Innovation Pharmaceuticals Inc (IPIX)

[PlentyParanoid]

That would be the time of last observation(s). Then comes possible transfer of data from local storage to final storage, double check for errors, outliers and hunting for missing data. All with some time needed to poke investigators to submit/check their data. Only when it is reasonably certain that all available info has been curated to a T and entered into database comes database freeze ie. data lock.

In case of IPIX prurisol trial it is even possible that CRO polished data from later part of the trial first and then went to curate and enter data from the early part of the trial. It looks like CRO gained full control of the trial only after half of it was already done.