Mymetics Corp (MYMX)

[bow-tie]

Anti-Cancer TLR3 Pathway: http://www.life-sciences-europe.com/organisation/tollys-2015-lyon-rhone-alpes-region-france-west-2001-38318.html

Vaccines with built-in immune response modi?ers, such as Toll-like receptor (TLR) ligands, may avoid such aberrant imprinting of the immune system.
Methods We developed reconstituted RSV envelopes (virosomes) with incorporated TLR4 ligand, monophosphoryl lipid A (RSVMPLA virosomes). Immune responses and lung pathology after vaccination and challenge were investigated in ERD-prone cotton rats and compared with responses induced by live virus and formaldehyde-inactivated vaccine (FI-RSV), a known cause of ERD upon RSV challenge.

https://onlinelibrary.wiley.com/doi/pdf/10.1111/irv.12112 Mymetics

TLR deficiency extends life expectancy in HD mice


https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857515/

TLR3 activation in the lung induces skeletal muscle adaptations and cachexia. https://www.ncbi.nlm.nih.gov/pubmed/29452288