Innovation Pharmaceuticals Inc (IPIX)

[MinnieM]

Edited... That's not at all how I view the sachets being developed. I should have used the company terms. Think of something that pours out with the texture of sugar, Emergen-C or something like that. Adding it to water creating a rinse.

http://www.ipharminc.com/press-release/2017/12/18/innovation-pharmaceuticals-brilacidin-oral-mucositis-program-moving-forward-based-upon-positive-anchoring-phase-2-results-and-increased-brilacidin-franchise-value?rq=sachet

Sachets, which people are very familiar with and use on an almost daily basis (e.g., sugar packets, artificial sweeteners) increasingly are being developed as a novel means of patient-friendly, drug delivery.

What you are describing sounds more like a lollipop or candy that melts in your mouth. Here's a better description by the company:

http://www.ipharminc.com/press-release/2018/3/15/innovation-pharmaceuticals-views-brilacidin-om-as-clearly-differentiated-compared-to-limited-competition-for-preventing-severe-oral-mucositis?rq=sachet

Summary Points

· Brilacidin-OM viewed by Company to have significant competitive advantages and less challenges than other OM drug candidates:

o Prevention: Effective reduction of SOM incidence, beyond providing symptom relief, would be a critical factor toward successful commercialization

o Delivery: Brilacidin-OM developed in sachet packets offers a portable, quick-mixing, “instant” oral rinse therapy—patients and providers likely would more readily adopt

o Cost: Brilacidin-OM avoids costly manufacturing and logistics of sterile IV therapy competitors amid a regulatory environment demanding lower drug prices

· Company preparing for U.S. Food and Drug Administration (FDA) meeting to discuss Brilacidin-OM development plan

Regarding compassionate use... the company doesn't have the funds to give it out. The fastest way to get it out to those in need is via ph4.





In Reply to 'kfcyahoo'
KarinCA,

I invision the sachets as a "hard candy" more than a liquid source. My understanding of OM is that not one case is the same as far as location s in the mouth(I think my mother had it the late 1980's, though the term OM was never used, she defintely had painful mouth sores after chemo t-ments and her meals were most often soup form, apple sauce-nothing solid). I would think the rinse and spit would touch most, if not all, of the inflamed areas of the mouth. Is ipix working on the sachet on the premise that the sachet will disolve in the mouth into liquid form and then the patient swishes and spits? Or does the patient swallow the sachet and it's absorbed into the body which targets the OM?

My wish is the fda considers the ph2b B-OM results worthy of compassionate use(it is life threating at stage 4). There's a company in Europe called myTomorrows, started by a doctor whose father passed from lung cancer. There are American companies who are participating. Link below.

https://mytomorrows.com/en/team/#the-team