Ayala Pharmaceuticals Inc (ADXS)

[mypekeispooped]

This may help, "... This usually begins with Phase IIa clinical trials, in which the goal is to obtain an initial proof of concept (POC). The POC demonstrates that the drug did what it was intended to do, that is, interacted correctly with its molecular target and, in turn, altered the disease. Phases I and IIa are sometimes referred to as “exploratory development” The Phase IIb trials are larger and may use comparator agents and broader dosages to obtain a much more robust POC."