Innovation Pharmaceuticals Inc (IPIX)

[PlentyParanoid]

If you are referring to my latest graph you so are badly off that you are not even wrong. I have to assume you don't understand. The graph is not based on IPIX trial but to about 15000 psoriasis subjects, including 6 arms with less than 30 subjects, 19 with less than 50 subjects etc. Jeez, TIAB the eminent clinical statistician, stop and think for once before wailing.

Here is a statement for you to chew:

In 199 psoriasis trial arms encompassing about 46000 subjects and including 18 arms with less than 30 subjects, 56 arms less than 50 subjects and 91 arms with less than 100 subject the highest reported sPGA 0 response with placebo is 1.8 % with standard deviation of 0.5 %. This makes me concluded that sPGA 0 response rate of 10.7 % reported for 200 mg arm in prurisol phase 2a trial is not a fluke attributable to placebo response because it presents more than 6 sigma deviation from the historical norm for the said response. A level of deviation that is considered a proof even in particle physics or cosmology. Furthermore, the graph in my previous post shows that the ratio of reported sPGA 0/1 and sPGA 0 responses for 200 mg dose in prurisol phase 2a trial is consistent with historical data.

As to what my graph says about response for 400 mg dose ... or when, if ever, we will see prurisol p2b results.. well, those I leave to others.