Mega Millions numbers for 05/22/2018 are: 16 17 21 36 48 Mega Ball 9 Megaplier is 3 There was no Grand Prize Winner. The estimated Grand Prize was $60,000,000 ($34,900,000 cash). The next drawing is on Friday, May 25th, 2018 with an estimated Grand Prize of $73,000,000 ($42,500,000 cash). http://www.megamillions.com/