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Re: ZeWaffleBaron post# 1318

Tuesday, 05/22/2018 11:52:24 PM

Tuesday, May 22, 2018 11:52:24 PM

Post# of 2022
Hey Buddy, hope all is well with you, the board has been kind of quiet but i suspect it will get busy as summer progresses.

Any thoughts on CEO comments about urinary stress incontinence indication and the potent effects on levator ani muscle ? I am hoping that we partner with a Pharma that sees the potential in VK5211 besides just the hip fracture.

"Scott Henry

Just a couple of questions, first with regard to 5211. What are your thoughts on potential stress urinary incontinence indication?

Brian Lian

It’s an interesting question. We have obviously generated, I think very compelling data in the setting of hip fracture. We know that this mechanism has shown some benefit in the setting of stress urinary incontinence. And there is no trial ongoing with another SARM in that setting. We find it really interesting and compelling opportunity. But I think our plan now is to continue the dialogue that we have with potential partners and see where those lead -- those conversations lead. And we’ll also be monitoring the progress with the other SARM and see what those data look like. And I believe that will be expected by the end of the year.

I will say it on the levator ani muscle, which is the muscle that many considered to be important in that setting, VK5211 has shown very potent effects. And so we do think that if the mechanism is validated in this next trial result, it would be really interesting for 5211. But at this point, the near-term plan is to certainly continue discussions with partners."
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