Biotech Values

[semi_infinite]

MYOK - LVEF is preserved and you wouldn't need to exclude anybody with less than 50% LVEF. RF catheter intervention is minimally invasive relative to myectomy, about the same as ASA. I am guessing it is less than a 2 hr procedure past the learning curve.

461 is still unproven wrt to long term side effects (beyond LVEF lowering seen in P1) and efficacy. If it is like other beta blockers wrt side effects, then there will be cross over to interventional procedure, either catheter or surgery. Also, don't know how much 461 will cost if is proven useful. Ablation would be a one time cost with ~$2k out of pocket cost depending on coverage.