Spectrum Pharmaceutecals Inc (SPPI)

[antihama]

The Share Price Continuum to $6B Pozi sales.

Pozi won’t get there overnight but it’s nice to know it’s potential in say 7 to 10 years. It first needs to get approved in NSCLC (in the US that’s about 2 yrs away). It will also need to start a basket study in those 20 cancer indications that Dr. Heymach talked about in the video (expected to start this year) and get approval for that. He felt confident that will happen giving examples of other TKIs targeting mutations successfully in other cancers e.g. B-RAF and ALK, etc. SPPI will need to run these studies, or probably more correct, its licensing partners will, in the EU and Japan. With every sign that becomes more of a certainty, the share price will rise. If you are not certain now, September’s WCLC when more mature data will be released will add so much more certainty. If you believe the MDA data released in April showing the 1st 11 EGFR patients still not reaching medium PFS after 6.6 months where 4 to 6 months is a homerun then the share price of Spectrum now is at fire sale prices. This share price is a godsend to small investors to get multiples on their investment but who have to take chances (risk of trial failing?) in order to stay ahead of the big boys who can instantaneously jump on the share price with any good news. A small investor who jumps in on good news (in Sept?) after the big boys jump in will make money but perhaps just make a half a multiple or so. I guess it depends on your level of risk taking on how you proceed. Another factor that will affect the sales projection is how long will mPFS be. Right now it’s at 6.6 months, say it settles at 8 months, that’s only 2/3 of a year so you will need to decrease that sales projection by a third, if it’s over a year you’ll need to increase accordingly. Licensing deals will weigh in on the share price as well as the licensing agreement with MDA where they got LOTS of incentive to mine their trove of data

patents related to exon 20 as well as any unidentified discoveries related to the use of poziotinib that may come from Dr. Heymach’s lab at MD Anderson in the future.

Reminds me of a football game where you sense that the momentum has changed and even though the team is behind, you know they are gonna win. It’s just a matter of time. I can wait, the pressure is not on me it’s on the naysayers. Laugh if you want but remember ‘he who laughs last, laughs best’!