Ayala Pharmaceuticals Inc (ADXS)

[jckrdu]

Something like this is probably the plan to control costs and move the company forward...

1. Prostate franchise - If combo results are good, joint partnership pursued with Merck to get the Phase 3 trial funded. If the results aren't good enough to get Merck interested in funding the Phase 3, this franchise should be shutdown quickly, IMO.

2. NEO franchise - This one is set with Amgen funding all clinical trial costs from this point forward. Advaxis gets development milestones (starting with 1st dosing $$$ milestone likely coming in May/June), so this is a cash-flow positive franchise for ADXS.

3. HPV Franchise - Ken needs to get the AXAL commercialization deal executed so ADXS gets 1) some upfront cash, and 2) milestone payments thus turning this into a cash-flow positive franchise.

4. HOT - Multiple INDs coming in 2018, per the corporate presentation. IMO, Ken will license at least 1 indication to bring in some upfront cash, and get a partner to help fund clinical development.

Not a bad situation, IMO. All doable decisions/actions this year: Make the decision on Prostate go-forward plans, get the AXAL deal done, and license at least 1 HOT construct.