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Monday, April 30, 2018 2:29:55 PM
Maybe that is why Rahul ex- Peregrine covering analyst that was with Noble Financial
Now, HS-110 may be a PS Targeting drug....is this possibly why Rahul stopped poppinv up at PPHM cc and also why Jeff Hutchins left and lands over at Heat Biologics... ?
HS-110 (viagenpumatucel-L)
Advanced Non-Small Cell Lung Cancer (“NSCLC”)
HS-110 utilizes ImPACT-modified lung cancer cells to stimulate a patient’s immune system to activate a cytotoxic T cell response against a range of antigens that are known to be expressed by a high proportion of patients with NSCLC. The backbone cell line for HS-110 was selected based on antigenic overlap with patient tumor specimens, including known antigens as well as many additional known and unknown antigens. This approach provides a significant advantage over single antigen approaches by reducing the risk of antigen-loss variants emerging post-treatment and by addressing the underlying genetic and antigenic heterogeneity within tumors.
Heat Biologics is conducting two clinical trials evaluating HS-110 for the treatment of NSCLC:
A multi-arm Phase 2 trial using HS-110 in combination with Bristol-Myers Squibb’s anti-PD-1 checkpoint inhibitor, nivolumab (Opdivo®). For more information reference study protocol NCT02439450 on clinicaltrials.gov.
A Phase 2 randomized, controlled trial using HS-110 in combination with cyclophosphamide. For more information reference study protocol NCT02117024 on clinicaltrials.gov.
http://www.heatbio.com/pipeline/hs-110
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....and Heat Biologics would require PS Targeting if they use "cyclophosphamide"
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=130082441
....which is why I think HS-110 may be PS Targeting
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