Friday, April 13, 2018 10:05:15 AM
Treatment with TyrNovo's NT219 in combination with targeted cancer drugs, as well as chemotherapy and immuno-oncology therapies, prevented acquired resistance and reversed resistance of colon, lung and head-and-neck cancers in patient-derived xenograft models.
TEL AVIV, Israel, April 13, 2018 /PRNewswire/ -- Kitov Pharma (NASDAQ and TASE: KTOV), today announced that TyrNovo Ltd., a company majority-owned by Kitov, will present pre-clinical data on TyrNovo's anti-tumor resistance drug candidate, NT219, in a poster session at the American Association for Cancer Research (AACR) Annual Meeting 2018, to be held on April 14-18, at the McCormick Place, Chicago, Illinois.
The poster highlights recent promising results, further demonstrating NT219's efficacy in synergy with immuno-oncology therapies. The recent results, achieved using double autologous PDX models, demonstrated that NT219 converted non-responding tumors to responders to pembrolizumab (Keytruda®). The models also demonstrated the efficacy of NT219 in enhancing the immunotherapeutic potential of cetuximab (Erbitux®).
Details on the poster presentations are as follows:
Session Title: Immune Mechanisms Invoked by Therapies 1
Session Time: 4/16/2018 1:00 PM - 5:00 PM ET
Location: Poster Section 33
Poster Board Number: 2754 / 16
http://kitovpharma.investorroom.com/2018-04-13-TyrNovo-to-Present-at-2018-Annual-Meeting-of-the-American-Association-for-Cancer-Research
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