Viking Therapeutics Inc (VKTX)

[Flubadub]

Would like to see thoughts on the recent JAMA study & article out Apr 5th about the link between muscle mass and survival rate in breast cancer and how it will relate to VK5211. Conclusions and link below...

Conclusions
We demonstrate that sarcopenia is not a condition restricted to patients with later-stage disease but rather is highly prevalent among patients with nonmetastatic disease across all levels of BMI. Our findings are likely generalizable across many other nonmetastatic cancers because the associations with muscle and improved survival for those with metastatic cancer has been observed across a variety of solid tumors. Additionally, information on muscle quantity and adiposity from clinically acquired CT scans provide significant prognostic information that outperforms BMI.21 Both muscle and adiposity represent modifiable risk factors in patients with breast cancer. In addition to weight loss, we should also consider interventions to improve muscle mass, such as resistance training or protein supplementation.22 In the era of precision medicine, the direct measurement of muscle and adiposity will help to guide treatment plans and interventions to optimize survival outcomes.

https://jamanetwork.com/journals/jamaoncology/fullarticle/2677300