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Re: A deleted message

Sunday, 03/25/2018 3:23:39 PM

Sunday, March 25, 2018 3:23:39 PM

Post# of 403752
I found one phase 4 study for ONLY MODERATE. I could not find any "MILD to MODERATE" trials. The problem with this example is that it is the 30mg twice a day dose that Otezla is famous for. Out of the 85 plus trials, they came up with that dose because it was most efficacious. So that throws everything out the window in comparison because Prurisol is not at the ideal dose --- all we have to hang our hats on is that 200mg looked much better than 50mg and 100mg. So now we move to 300mg and 400mg knowing that Prurisol is safe into the 600mg range I believe.

I have to go to work now so have fun looking at these results for just MODERATE and IGA scale.

https://clinicaltrials.gov/ct2/show/results/NCT02425826?term=Apremilast&draw=2&rank=9§=X90156