Innovation Pharmaceuticals Inc (IPIX)

[PlentyParanoid]

Yeah. Let me give you an example of ridiculously good.

Recently Celgene reported results from p2 trial for Otezla in ulcerative colitis. The results were considered good with 18 out of 57 subjects having a clinical remission with p < 0.05 against placebo. Brilacidin posted a clinical remission rate of 10 out 15 subjects in UP, a closely related ailment - location of inflammation being the major difference.

It looks like B has minuscule absorption thru mucosa which should take care of all those pesky (an mostly unfounded) inhibition worries on systemic level. They stay in the gut with B, so to speak.

So, IPIX needs only to find an oral formulation for 100 mg of Brilacin that delivers the stuff into intestines and they might have a ridiculously potent UC drug in their hands.

BTW. Dr. Fisher tells that probability for Brilacidin remission rate in UP being superior to Otezla's in UC is about 99.1 %. There! (my guess is that Infinity will find something to complain about that) If I were the management in IPIX I would not waste my time with psoriasis drug that, at best, will be a middle of the pack runner. I would go with B all the way to Lenox Hill or Hart Island. Which ever it turns out to be.