Catalent Inc (CTLT)

[Trend-Setter]

Good News yesterday!
"Biohaven has been working with Catalent U.K. Swindon Zydis Limited, a subsidiary of Catalent, Inc. (NYSE: CTLT) ("Catalent") to develop a new ODT formulation of rimegepant which dissolves on the tongue without the need for fluid intake."
https://ih.advfn.com/p.php?pid=nmona&article=76833940

Same thing will happen to vaccines. Mymetics and 4 consortium partners are pioneering this disruptor in the vaccine industry worldwide.

"Vaccines are often produced as liquid biological products containing > 80% of water, which explains in part their instability during the storage in laboratories, hospitals, or manufacturing facilities. Liquid vaccines are inherently prone to physical and/or chemical modification, and degradation might also affect the immunological properties of the vaccine immunogens, with unwanted immune responses or insufficient immune protection. There is growing evidence that solid vaccine forms (e.g. powder) may offer several advantages over the liquid formulations, such as slowing down modifications and degradation.
The vaccine industry has developed freeze-drying lyophilization with low residual moisture content for improving stability and extending vaccine shelf-life. Such vaccines are stored as stable lyophilized dry products in a continuously frozen state at < -18°C, while others can be stored in refrigerators (+2-8°C). Therefore, maintenance of the cold chain is fundamental for preserving the bioactivity of most liquid and lyophilized vaccines currently on the market as well as those under development. However, many regions of developing countries also lack electricity and cooling capability for keeping vaccines below +8oC. The development of cold-chain independent vaccines in solid powder forms may greatly simplify the logistics and represent one of the long-term global solutions for addressing important issues faced by the vaccine field."
" Due to superior stability and the ease of administration of future solid vaccine forms for non-invasive routes, the world vaccine market landscape is expected to change. Thermostable solid vaccine forms developed for needle-free mucosal administration are expected to gradually replace the liquid and lyophilized/reconstituted vaccines administered by needle/syringe injections. Thus, such new thermostable solid vaccines will contribute to higher immunization coverage for the great benefit of the overall health care system."

https://cordis.europa.eu/result/rcn/194900_en.html

This project ends this year and final result is imminent!