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Re: frrol post# 219407

Thursday, 03/01/2018 1:03:39 PM

Thursday, March 01, 2018 1:03:39 PM

Post# of 403092
IPIX has about 80 subjects both in 300 mg and placebo arms and about 30 subjects in 400 mg arm. Assuming that the placebo arm behaves and has a PASI75 response around 10 % then 25 % or better PASI response rate in 300 mg arm would be success in statistical sense (p < 0.05). 400 mg arm would require PASI75 response rate at about 27 % or better. Both very doable in my opinion.
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