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Re: Investintin post# 284767

Tuesday, 02/27/2018 1:17:09 PM

Tuesday, February 27, 2018 1:17:09 PM

Post# of 402518

Hahaha wow!!








Yep, that was exactly what the FDA said to Kempharm when they requested an abuse deterrent label for their prodrug, Apadaz. If you know of any pro-drug opioids that actually work as intended and are abuse-deterrent, please share.





Kempharm's studies show that there is a decrease in plasma concentration when *EIGHT* (8!!!) tablets are taken. In other words, not much help




I thought preventing dead by lowering the concentration in plasma was good... I guess I was wrong ;)





So by the standards you describe, a drug should be described as having overdose protection if there is no change for the first 7 tabs and a mild reduction in plasma conc if an 8th tab is taken. Got it. Good luck with your investment.






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