Friday, February 23, 2018 4:33:33 PM
From the 10-Q:
Guess what that means for the size distribution of the resultant nanomicelles made from said uniformly sized backbone polymers?
They say reproducibly making the ligands and scaling up that process should be relatively easy.
The key could be reliably attaching the ligands to the functional groups of the backbone polymer / nanomicelle with some uniformity, or less likely getting the nanomicelle to form uniformly with the functional groups evenly spaced out. I'm not sure how many ligands need to be present and how evenly spaced in order to attach the numerous viral coat proteins and tear it apart.
Seymour made it sound like it was "shake and bake," but that appears not to be the case. Someone else may have said something similar, but that information source is also unreliable.
From the patent https://patents.justia.com/patent/20100008938:
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