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Re: frrol post# 218761

Friday, 02/23/2018 12:56:07 PM

Friday, February 23, 2018 12:56:07 PM

Post# of 402961
The outcomes were primarily to gather more data on all measures and to better characterize MOA. For all outcomes endpoints were met and outcomes achieved. Please note the trial design did not include efficacy measures regarding direct apoptosis, rather measures applied to p53 repair and modulation as efficacy. Mistaking p53 efficacy for tumor reduction as the only meaningful efficacy outcome is very common misperception in the ongoing discussions here.
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