Athersys Inc (ATHXQ)

[Murph1953]

January 18, 2018

Researchers create first stem cells using CRISPR genome activation

"This is a new way to make induced pluripotent stem cells that is fundamentally different from how they've been created before,"

"Pluripotent stem cells can be turned into virtually any cell type in the body. As a result, they are a key therapeutic resource for currently incurable conditions, such as heart failure, Parkinson's disease, and blindness.


https://www.sciencedaily.com/releases/2018/01/180118162449.htm
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Harvard researchers genetically ‘edit’ human blood stem cells

"HIV specifically targets T cells, enters via a gene receptor called CCR5 that serves as a doorway into the cells

"...Using the CRISPR/Cas gene-editing technology, the Cowan and Rossi teams knocked the CCR5 receptor out of blood stem cells..
https://hsci.harvard.edu/news/harvard-researchers-genetically-%E2%80%98edit%E2%80%99-human-blood-stem-cells
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Protein Switch For Functional Insulin-producing Cells Found

"For more than a decade, scientists across the globe sought to replace failing pancreatic beta cells linked to immune destruction in children (type 1 diabetes) or obesity-associated diabetes in adults (type 2 diabetes). Although cells made in a dish were able to produce insulin, they were sluggish or simply unable to respond to glucose....

"Start With Induced Pluripotent Cells

https://reliawire.com/protein-switch-insulin-cells/?utm_source=TrendMD&utm_medium=cpc&utm_campaign=Reliawire_TrendMD_1
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Discovery may make it easier to develop life-saving stem cells

".. just now figuring out how adult somatic cells such as skin cells can be turned into embryonic stem cells.

"Japanese researchers found that by introducing four other genes into cells, stem cells could be created without the use of a human egg. These cells are called induced pluripotent stem cells, or iPSCs.

"This is important because the iPSCs are derived directly from adult tissue and can be a perfect genetic match for a patient,"

https://www.sciencedaily.com/releases/2014/07/140717180534.htm
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Skin cells transformed into functioning liver cells in mouse study
https://www.sciencedaily.com/releases/2014/02/140223131703.htm
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FDA Approved Cellular and Gene Therapy Products
https://www.fda.gov/biologicsbloodvaccines/cellulargenetherapyproducts/approvedproducts/default.htm