Synaptogenix Inc (SNPX)

[InTheTrenches]

I believe we will see NTRP raise money over the next several months. There are several ways to accomplish this:

- A dilutive financing (Perhaps 3M shares at $6.50/share?)
- A partnership for Bryostatin in another country (e.g. Japan) with upfront money
- A partnership on one of the other indications (Fragile-X, APOE4, or TBI) with upfront money

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The most attractive way to raise capital might be a partnership for Bryostatin in a country like Japan, for all indications, for ~$50M upfront and a 10% royalty.

By raising significant capital, we can progress our business development including:

- Trial runs of manufacturing synthetic Bryostatin
- Buildout of manufacturing capacity for synthetic Bryostatin
- Initiate a Phase 1/2 trial in Fragile-X
- Initiate a Phase 1/2 trial in APOE4
- Initiate a Phase 1/2 trial in TBI
- Work on an alternative to IV infusion (either IM or oral delivery)
- Preclinical work on other potential drugs that activate PKC-e, including bryologs

I also think it's important that we complete the proposed phase 2 trial in AD with ~ 1 year of cash in the bank, leaving us in strong cash position for negotiating a partnership with a major pharma next year.

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Does anyone have any insights on the new president's ability to negotiate partnerships?