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Re: kfcyahoo post# 214106

Thursday, 01/25/2018 10:11:38 AM

Thursday, January 25, 2018 10:11:38 AM

Post# of 403226
brodalumab is approved in US in second line for moderate to severe psoriasis. Valeant got approval from FDA Feb 17 2017.

In three trials with subjects having moderate to severe psoriasis about 85 % of brodalumab subject scored PASI 75 response. BUT
1. Brodalumab is administered by injection
2. Brodalumab is immunosuppressant (and seriously so)
3. Brodalumab has a FDA black box warning about induced suicidal tendencies

That 3rd point is a real baddie marketing wise.
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