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Re: gestalt2 post# 19439

Friday, 01/19/2018 3:24:32 PM

Friday, January 19, 2018 3:24:32 PM

Post# of 217058
I too believe that the P3 data will be good. I just went and looked at the past Mono studies again, and it looks like the viral load dropped significantly on each of the three varied doses significantly enough to show the 70% they are looking for the combo data. Granted it was only for 34 patients and 10 on placebo. Although I'm not sure how it will react with the other HAART combo drugs that it is paired with. I am more curious where the mono data will be read out...that one could erase all the HAART drugs for good, and present CYDY with a 100B payout! Just my two cents.

Arm 1
PRO 140 - 162 mg for three single SC doses: Days 1, 8, and 15

Arm 2
PRO 140 - 324 mg for three single SC doses: Days 1, 8 and 15

Arm 3
PRO 140 - 324 mg for two single SC doses: Days 1 and 15 plus one SC dose of placebo at Day 8

Arm 4
Placebo for three single SC doses: Days 1, 8 and 15

Participants Analyzed
[Units: Participants]

11 11 12 10

Maximum Change in Viral Load Following Initiation of Treatment (Viral Load is Defined as HIV-1 Copies/mL and Expressed as log10 Copies/mL).
[Units: Log10copies/HIV-1 RNA/mL]
Mean (Standard Deviation)
-0.99 (0.558) -1.65 (0.571) -1.37 (0.891) -0.23 (0.285)

In My Own Personal Opinion Of Course!

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